Peptidoglycan Contribution to the B Cell Superantigen Activity of Staphylococcal Protein A
ABSTRACT Staphylococcus aureus causes reiterative and chronic Picture Frame persistent infections.This can be explained by the formidable ability of this pathogen to escape immune surveillance mechanisms.Cells of S.aureus display the abundant staphylococcal protein A (SpA).SpA binds to immunoglobulin (Ig) molecules and coats the bacterial surface t